Pleiotropy occurs when one gene influences two or more seemingly unrelated phenotypic traits. Such a gene that exhibits multiple phenotypic expression is called a pleiotropic gene. Mutation in a pleiotropic gene may have an effect on several traits simultaneously, due to the gene coding for a product used by a myriad of cells or different targets that have the same signaling function. Pleiotropy can arise from several distinct but potentially overlapping mechanisms, such as gene
Pleiotropy definition, the phenomenon of one gene being responsible for or affecting more than one phenotypic characteristic. See more.
Steroid drugs, such as prednisone and prednisolone, have pleiotropic effects, including systemic ones, for the same reason that endogenous steroid hormones do too: cells throughout the body have receptors that can respond to them, because the endogenous ones are endocrine messengers. 2021-04-13 · Pleiotropy definition: the condition in which a single gene exerts simultaneous effects on more than one | Meaning, pronunciation, translations and examples Pleiotropic: Producing or having multiple effects from a single gene. For example, the Marfan gene is pleiotropic, potentially causing such diverse effects as long fingers and toes (arachnodactyly), dislocation of the lens of the eye, and dissecting aneurysm of the aorta. (genetics) The influence of a single gene on multiple phenotypic traits; pleiotropism. Antonym: polygeny· (pharmacology) The existence of drug effects other than the one for Video shows what pleiotropic means. of or pertaining to pleiotropy. Pleiotropic Meaning.
The influence of a single gene on multiple phenotypic traits; pleiotropism · pleiotropy(Noun). The existence of drug effects other than the one for the appropriate answer is always 'What do you mean?'. Multiple traits, multiple meanings. Pleiotropy refers to the phenomenon of a single gene affecting Pleiotropy occurs when one gene influences two or more seemingly unrelated phenotypic traits. Such a gene that exhibits multiple phenotypic expression is 18 Dec 2019 Antagonistic Pleiotropy (AP) is today the best-accepted theory for the temporal pattern of population diversity, fitness, and mean life history, If the goal is to estimate the pleiotropy of null mutations to answer questions about evolution, then those mutations too pleiotropic to ever contribute to evolution are 11 Mar 2013 Statins have pleiotropic effects-that is, they are simultaneously capable of producing more than one benefit, and in cardiovascular risk reduction, 12 Oct 2019 Get Notes Here - https://payments.pabbly.com/subscribe/ 5e2954ad14a2e43f1110d5ef/notesClass: 12thSubject: BiologyChapter: Principles of pleiotropy - Meaning in Tamil, what is meaning of pleiotropy in Tamil dictionary, pronunciation, synonyms and definitions of pleiotropy in Tamil and English. Pleiotrophy - definition. Pleiotropy occurs when one gene influences two or more seemingly unrelated phenotypic traits.
Definition of pleiotropy in the Definitions.net dictionary. Meaning of pleiotropy. What does pleiotropy mean? Information and translations of pleiotropy in the most comprehensive dictionary definitions resource on the web.
av T Ekbom · 2005 · Citerat av 23 — characteristics for a well-designed material can be defined in terms of the amount of absorbed hydrogen, the binding energy of the hydrogen and finally the av M Beato · 2000 · Citerat av 821 — became the first molecularly-defined transcription factors for. RNA polymerase II fermenting (SWI/SNF) complex, a set of pleiotropic transactivators that In this present study we have defined the range of proteins that aggregate in yeast cells during normal growth and after exposure to stress conditions including av L Krubitzer · 2007 · Citerat av 217 — control a number of activities in development (pleiotropy; Hall, 1994), (I use the term epigenetic to mean a characteristic or feature resulting dogs appears to be affected by pleiotropy and are both inherited by means elimination of this trait is unlikely due to pleiotropic interactions. The author then discusses the Pleiotropic Paradox and the development of the promotes glutathione synthesis intracellularly through physiological means. [arv], dessa egenskaper kommer alltid att visas tillsammans och kan verkar således vara korrelerade ".
Changes in proteins are less likely to underlie such changes because most regulatory proteins are constrained due to their pleiotropic roles in the development of different structures. A Decade Spanning Single Exchange. This may be an important pleiotropic effect whereby rosuvastatin reduces mortality in patients with coronary artery disease.
Understanding how these variants impact on disease isn’t easy, as genes are often pleiotropic, meaning that they produce multiple effects in the body. And as the authors pointed out, Pleiotropic Effects of Statins . The word pleiotropic originally referred to a gene that influenced or affected more than one trait in an organism, several phenotypic expressions.
In human beings pleiotropy is exhibited by syndromes called sickle anaemia and phenylketonuria.
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Pleiotropy can arise from several distinct but potentially overlapping mechanisms, such as gene Definition of pleiotropy. genetics. : the phenomenon of a single gene influencing two or more distinct phenotypic traits : the quality or state of being pleiotropic In genetics, there's a concept called pleiotropy, which posits that a single gene can influence multiple traits. [Steven] Tanksley suggests there's substantial evidence that at least 2019-07-11 · Pleiotropy is the expression of multiple traits by a single gene.
In the context of life history evolution, pleiotropy means that a single gene affects the fitness
Pleiotropy is a genetic disorder caused when one gene influences two or more apparently unrelated phenotypic traits. Explore more about Pleiotropy at BYJU'S. Pleiotropy is the well-established phenomenon of a single gene affecting multiple traits.
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PLEIOTROPY Meaning: "production by a single gene of two or more apparently unrelated effects," 1921, from German pleiotrop… See definitions of pleiotropy.
2019-07-11 Definition of pleiotropy. genetics.
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The gene controlling starch synthesis in pea shows a small degree of pleiotropy. Starch synthesis in pea seeds is controlled by one gene. It has two alleles B and b
American Heritage® Dictionary of the English Language, Fifth Edition. Pleiotropism is a central term in developmental genetics. In pleiotropism, a single gene affects a number of phenotypic traits in the same organism. These pleiotropic effects often seem to be unrelated to each other.
Definition. Med blodfettsrubbning menas förhöjda kolesterol- och/eller (pleiotropic) effects of statins in the management of acute coronary syndromes. J Am.
Pleiotropic Meaning. How to pronounce, definition audio dictionary. How to say pleiotrop What is the definition of pleiotropic? What is the meaning of pleiotropic? How do you use pleiotropic in a sentence? What are synonyms for pleiotropic?
In pleiotropism, a single gene affects a number of phenotypic traits in the same organism. These pleiotropic effects often seem to be unrelated to each other. The production of diverse effects, especially the production by a single gene of several distinct and seemingly unrelated phenotypic effects.